VX-770 Size:2mg solid Epetraborole was in development for

Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens

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Hildebrand J

FT-0700250

2019 Feb 21

VX-770 Size:2mg solid Epetraborole was in development forVX 770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 45% cases of cystic fibrosis, and is included in a combination drug, lumacaftor ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel